Aspirin-exacerbated respiratory disease: not always “adult-onset”.

Aspirin-exacerbated respiratory disease: not always “adult-onset”.

The AERD Center at Brigham and Women’s Hospital in Boston, MA collected a detailed clinical history from 227 patient with AERD within their AERD Patient Registry. Although AERD is generally considered to be a disease that begins only in adults, 3.5% of the patients (8 of 227) reported that they developed nasal polyps and AERD before the age of 18. This publication presents three pediatric cases of AERD who each developed the full triad of AERD/Samter’s Triad symptoms at the ages of 11, 8, and 13 years old. These cases and review of the AERD Patient Registry illustrate that the diagnosis of AERD must also be carefully considered in children who present with these symptoms.