Patients with AERD who develop a skin rash and gastrointestinal symptoms with aspirin desensitization produce large amounts of prostaglandin D2.

Prostaglandin D2: A dominant mediator of aspirin-exacerbated respiratory disease. The AERD Center at Brigham and Women’s Hospital in Boston, MA collected clinical characteristics and biologic specimens from 29 patients with AERD undergoing an aspirin desensitization procedure. In addition to the…

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