Tobacco smoke and AERD / Samter’s Triad

Smoking, environmental tobacco smoke, and aspirin-exacerbated respiratory disease.

A study published in 2012 by a group of researchers at the Scripps Clinic in California found that childhood exposure to environmental tobacco smoke was associated with increased odds of developing AERD, and the effect was even greater if there was also exposure to tobacco smoke during adulthood. This study, of 260 patients with AERD and matched controls, suggests that environmental tobacco smoke is at least one contributor to the development of AERD/Samter’s Triad.