This study has now been completed and is closed. We found that the prevalence of alcohol-induced upper (runny nose and/or nasal congestion) respiratory reactions in patients with
AERD was 75% and the prevalence of alcohol-induced lower (wheezing and/or shortness of breath) respiratory reactions in AERD was 51%. These reactions were generally not specific to one type of alcohol and often occurred after ingestion of only a few sips of alcohol. Therefore we concluded that alcohol ingestion causes respiratory reactions in the majority of patients with AERD, and clinicians should be aware that these alcohol-induced reactions are significantly more common in AERD than in controls who are aspirin tolerant.
The results of the study have been published in the Journal of Allergy & Clinical Immunology: In Practice, and are available here: