This manuscript from the Scripps AERD Center in California gives an all-encompassing picture of Aspirin-Exacerbated Respiratory Disease. In this comprehensive review, Drs. White and Stevenson aim to educate readers on the history of AERD, classical reactions to NSAIDs, diagnosis, prevalence of the disease, and available medical & surgical treatment. It is heartening to see the New England Journal of Medicine highlight this important disease since awareness is one of the greatest barriers to care in AERD. The Scripps Clinic in La Jolla, CA has a very active AERD Center. To learn more about them and their research head over to https://goo.gl/vD51CB.