Perspective from Dr. Laidlaw on the use of Aspirin Desensitization vs. Biologics for patients with AERD

As the director of one of the largest evaluation and treatment centers for patients with AERD in the world, Dr. Laidlaw is often asked how to approach the use of aspirin desensitization followed by high-dose aspirin therapy for patients with AERD in the current age of newly available biologics. In this perspective article, she describes a place for both treatment modalities, sometimes even both in the same patient at the same time. It is a set of decisions that need to be made on an individual patient basis — efficacy, safety, cost, and patient preference should be considered when approaching the decision and recommendation.