Chronic rhinosinusitis with nasal polyps (CRSwNP) is a complicated disease with no definitive cure. As with other complex diseases, experts largely agree that a multidisciplinary approach is the most beneficial for patients. We recommend that patients with CRSwNP seek care from both an allergist/immunologist and otolaryngologist. The allergist/immunologist can diagnose and manage the disease and other co-morbid conditions while the otolaryngologist can perform nasal endoscopies, biopsies and surgery if needed. In the case of aspirin-exacerbated respiratory disease (AERD), aspirin desensitization is often recommended after surgery to increase success and prevent the polyps from recurring. Collaboration between allergists/immunologists and otolaryngologists gives a well-rounded, patient-centered approach to effectively manage CRSwNP. More information about the benefits of a multidisciplinary approach can be found here.